Dr. Thomas Seyfried’s “The Metabolic Approach to CancerImagine your body as a well-organized society, where each cell plays a specific role. Cancer disrupts this harmony, as a group of cells goes rogue, breaking the rules of normal growth and function. These renegade cells multiply uncontrollably, forming tumors that invade and damage surrounding tissues. Origins of the Word… Read More: Uncovering the Preventable and Treatable Truths with Dr. Thomas Seyfried” explores the potential of a ketogenic diet1. Simple Definition: Imagine your body is like a hybrid car with two fuel tanks: one for gasoline (sugar) and one for electricity (ketones). The ketogenic diet, or keto diet, is like switching your car’s engine to run primarily on electricity. This means you drastically reduce your intake of carbohydrates… Read More in managing cancer. He emphasizes the importance of understanding the metabolic originsWhat is an origin? An origin is the starting point, the place or source where something begins. It’s like the very first chapter in the story of that thing. Examples: • The origin of a river: Where the river first starts to flow, like from a spring or a melting… Read More of cancer and focusing on preventing the fermentation“Ferment” describes a process where microorganisms like bacteria, yeast, or mold break down organic substances (often carbohydrates) in the absence of oxygen. This breakdown creates a variety of products, including acids, gases (like the bubbles you see in some fermented foods), and sometimes even alcohol. While fermentation isn’t directly involved… Read More process driving cancer and overcoming it. Seyfried emphasizes the need for magnesiumMagnesium is a superhero among minerals! It’s a shiny, silvery metal found abundantly in nature, but in your body, it acts more like a tiny maestro, conducting hundreds of essential metabolic reactions. • Synonyms: Well-documented synonyms for magnesium include: • Mg (chemical symbol) Etymology (Word Origins) • “Magnesium” comes from “Magnesia,”… Read More supplementation due to depletion in the food supply, as it supports different tissues in different ways. Calorie restriction in mice had a profound effect on blood vesselsBlood vessels are like tiny pipes or tubes that create a transportation network throughout your body. They carry blood, which delivers essential nutrients and oxygen to your cells and removes waste products. Think of them as the highways and roads that supply your body’s cells with fuel! • Other Names:… Read More and tumorA tumor is a lump or abnormal mass of tissue that grows in the body. It’s like a bump that shouldn’t be there. While some tumors are harmless, others can be serious and even life-threatening. Here’s a breakdown to help you understand them better: The Root of the Word: The… Read More cellsThe cell is the basic building block of the human body, a tiny, microscopic (too small to see without a magnifying tool like a microscope) unit that works together with billions of other cells to form every part of the body, from the skin to the heart. Each cell is… Read More, and managed epileptic seizures. Cancer is a metabolic disease, not a genetic one, challenging conventional views. Biomarker changes in the body tracked tumor growth and metastasis, and disturbed energy metabolismMetabolism is the set of chemical processes that happen inside the body to keep it alive and working. Think of the body as a busy kitchen where food is turned into energy, building blocks, and waste. These processes break down food to release energy, build new cells, and remove unwanted… Read More causes genetic abnormalities. Ketogenic diet effectiveness is not limited to specific types of cancer or stages. Measuring bloodBlood is the life force coursing through your veins and arteries, delivering vital oxygen and nutrients to every cell in your body while whisking away waste products. It’s a complex, dynamic fluid—not just a simple red liquid. Consider it a bustling highway system within your body, carrying various cellular vehicles… Read More ketonesKetones, organic compounds produced by the liver, are the unsung heroes of energy metabolism, stepping in when glucose, the body’s primary fuel, becomes scarce. Think of them as a reserve power generator, kicking into gear when the main power supply (carbohydrates) is low. While often associated with the ketogenic diet,… Read More and glucoseGlucose, a simple sugar (a sweet substance the body uses for energy), serves as a vital component in the human body, acting as the primary fuel for cells (tiny units that make up the body). Imagine the body as a bustling factory, where glucose is like the electricity powering the… Read More levels can help manage cancer treatment, and maintaining a ratio of glucose to ketones at 1.0 or below can hinder tumor cell growth. Therapeutic ketosisUnleashing the Power of Therapeutic Ketosis: A Deep Dive Imagine your body as a car with a dual-fuel engine. It can run on either gasoline (glucose from carbohydrates) or electricity (ketones from fat). Therapeutic ketosis is like intentionally switching your body’s engine to run primarily on electricity, a state where… Read More enhances drug effectiveness and reduces toxicity“Toxic” means something that’s poisonous or really harmful. It’s like something bad that can make you sick or even hurt you. Where did the word come from? A long, long time ago, people who used bows and arrows would put poison on the arrow tips to hunt animals or fight… Read More, and combining a ketogenic diet with drugs can significantly enhance their effectiveness and reduce required dosages.

Research shows a threefold increase in drug delivery to brain tumors with a ketogenic diet, potentially offering targeted cancer treatment with minimal toxicity. Cancer cells rely on fermentation for energy, driven by glucose and glutamineGlutamine is the most abundant amino acid in your body, meaning it’s a crucial component of the proteins that make up your muscles, tissues, and organs. But glutamine’s role goes beyond just being a building block. It’s also a versatile energy source for certain cells, especially those in your gut… Read More, and maintaining healthy mitochondria through diet and lifestyle can reduce the likelihood of cancer. Aboriginal tribes and traditional groups show extremely rare cases of cancer due to their healthy diet and lifestyle. Blood markersThe word “marker” has a rich history and multiple meanings, but in the context of the human body or living organisms, it typically refers to an indicator or signal that provides information about something else. Here’s a breakdown: Etymology and Origin: • Marker: This word likely emerged around the 14th… Read More provide insights into metabolic health and disease risk, and a Paleolithic diet with minimal processed foods and high carbohydratesCarbohydrates, often called carbs for short, are organic molecules that your body uses for energy. They’re one type of fuel the body can use for energy. Carbohydrates are made up of carbon, hydrogen, and oxygen atoms, hence the name “carbohydrate” (carbo = carbon, hydrate = water). They come in simple… Read More aligns with reduced cancer risk.

Metabolic treatment has extended the lives of terminal cancerWhat does “terminal” mean in medicine? In medicine, “terminal” describes an illness that doctors believe will eventually lead to a person’s death. There is currently no cure or treatment available that can stop the illness from progressing. Here’s an analogy: Imagine you’re lost in a maze. A “terminal” illness is… Read More patients, but a lack of funding and awareness hinders widespread adoption. Doctors lack understanding of cancer biologyBiology is the study of life! It’s the science that looks at all living things, from tiny bacteria to giant whales, and tries to figure out how they work, how they’re related, and how they change over time. Think of it like this: • Living things are like complex machines, made… Read More and focus on genetic targets in cancer treatment, which has limitations and risks. Adapting diets for metabolic treatment is crucial for personalized cancer treatment, and physicians need to retrain and work with a team to implement metabolic treatmentsImagine your body is a complex machine, with metabolism as its engine, transforming food into energy. Metabolic therapy is a revolutionary approach to health and disease management that fine-tunes this engine, optimizing its function for optimal well-being. It’s like a personalized tune-up for your body, tailored to your unique needs… Read More effectively.

Understanding patient metabolism is crucial for personalized cancer treatment, and fastingFasting simply means abstaining from food, and sometimes drinks, for a set period. It’s a practice observed across cultures and throughout history, for various reasons. What is fasting? Think of fasting as giving your body a break from eating. Instead of using the food you just ate for energy, your… Read More and ketogenic diets can optimize metabolic function and potentially have anti-cancer benefits. Processed carbohydrates drive blood sugarBlood sugar, also known as blood glucose, is a type of simple sugar circulating in your bloodstream. It can be a primary source of energy for your cells. Your body can get blood sugar from carbohydrates that you eat. The Word “Blood Sugar” This term is a modern invention, emerging… Read More constantly, and chronic exposure to certain foods can create a specific state in the body.

Video Chapters

00:01 Managing cancer by transitioning the body to fatty acids and ketones.

• Understanding the metabolic origins of cancer is crucial for effective management without toxicity.
• Dr. Thomas Seyfried’s research focuses on preventing the fermentation process that drives cancer and how to overcome it.

02:24 Magnesium supplementation for optimal health

• Dr. Seyfried emphasizes the importance of magnesium in our diet and the need for supplementation due to depletion in the food supply.
• Magnesium supplementation can benefit individuals who are stressed or training hard, as it supports different tissues in different ways.

06:49 Calorie restriction in mice had a profound effect on blood vessels and tumor cells, and managed epileptic seizures.

• Low steady blood sugarSugar is a substance represented as a simple carbohydrate (a basic type of molecule made of carbon, hydrogen, and oxygen) that serves as a vital component throughout the body. It is the primary source of energy for most cells, acting like the body’s main fuel. Every part of the body,… Read More seemed to help manage epileptic seizures in both children and mice.
• Children and mice with insulinYour pancreas produces the super hormone insulin, which is essential to your body’s metabolism. Here’s a breakdown to make it clear: Definition: Insulin acts like a master key that unlocks the door for sugar (glucose) to enter your cells. Glucose is the main source of energy for your body, and… Read More insensitivity due to high fatThe substance known as fat occupies a role far more complex and vital than often perceived. While frequently discussed in terms of diet and appearance, this tissue, properly termed adipose tissue when referring to the cellular mass, is a dynamic and essential component supporting a myriad of the body’s critical… Read More intake were unable to manage their epileptic seizures.

09:09 Cancer is a metabolic disease, not a genetic one, challenging conventional views.

• Biomarker changes in the body tracked tumor growth and metastasis.
• Disturbed energy metabolism causes genetic abnormalities, challenging current cancer treatment approaches.

13:40 Balancing act of not disturbing natural development while preventing breakthrough seizures

• Nutritional capabilities of the diet can be undermined if it is too aggressive
• Ketogenic diet effectiveness is not limited to specific types of cancer or stages

15:54 Measuring blood ketones and glucose levels can help manage cancer treatment.

• Using a meter like the Keto Mojo can provide constant ketosisA Deep Dive into the Metabolic State Transforming Health and Wellness Imagine your body as a hybrid car, capable of running on two distinct fuel sources: gasoline (carbohydrates) and electricity (fat). Ketosis is like switching your body’s engine from gasoline to electricity, primarily using fat for fuel instead of carbohydrates…. Read More measurements.
• Maintaining a ratio of glucose to ketones at 1.0 or below can hinder tumor cell growth.

19:56 Therapeutic ketosis enhances drug effectiveness and reduces toxicity

• Proper use of therapeutic ketosis can lower drug dosages and address toxicity issues.
• Combining ketogenic diet with drugs can significantly enhance their effectiveness and reduce the required dosages.

22:02 Ketogenic diet facilitates delivery of small moleculesImagine tiny building blocks that come together to form everything around you, from water to air to your own body! A molecule is a group of two or more atoms held together by strong forces called chemical bonds. Think of them as the microscopic Legos that build the world! The… Read More through blood-brain barrier

• Research showed threefold increase in drug delivery to brain tumors with ketogenic diet
• Potential for targeted cancer treatment with minimal toxicity

26:15 Cancer cells rely on fermentation for energy instead of oxygen.

• This is a result of a long-termChronic simply means “happening over a long period of time” or “of long duration.” Imagine a situation that keeps going on and on, unlike something short-lived. • Other Names: You might not encounter many other terms for chronic in everyday conversation. In some specific contexts, terms like “long-term” or “persistent”… Read More shift from oxidative phosphorylationOxidative Phosphorylation: The Body’s Power Plant Energizing Life: Understanding Oxidative Phosphorylation (OXPHOS) Have you ever wondered how your body transforms the food you eat into the energy you need to move, think, and simply exist? It’s a complex process, but a key player in this energy conversion is oxidative phosphorylation… Read More to substrate level phosphorylation.
• Cancer cells from various organsIn the context of the body, an organ is a distinct part made up of different tissues (groups of similar cells working together) that are organized to perform one or more specific functions. Familiar examples of organs include the heart, which pumps blood; the lungs, which facilitate breathing; and the… Read More all exhibit similar fermentation behavior.

28:10 Glucose and glutamine are the primary fuels driving cancer metabolism.

• Cancer cells require an abundance of glucose and glutamine in the microenvironmentUnveiling the Microenvironment: Your Body’s Inner Ecosystem Imagine your body as a bustling city, teeming with trillions of cells. Each cell resides in its own neighborhood, a microenvironment, where it interacts with its neighbors and the surrounding surroundings. Just like a neighborhood influences the lives of its residents, the microenvironment… Read More to drive fermentation.
• Intermittent hypoxiaHypoxia, a condition characterized by insufficient oxygen levels in tissues, is a critical threat to cellular health and function. Imagine your body as a bustling city, with oxygen as the essential fuel powering its activities. Hypoxia is like a power outage, disrupting the city’s operations and potentially leading to widespread… Read More can chronically damage oxidative phosphorylation, leading to the transition to fermentation metabolism in cells.

32:12 Optimizing mitochondrialMitochondria, often called the powerhouses of the cell (tiny units that make up the body), are vital structures inside cells that produce energy to keep the body functioning. Picture the body as a busy factory, where mitochondria are like generators, tirelessly converting food into energy that powers every organ, from… Read More function can reduce the body’s likelihood of switching to fermentation processes.

• Highly aerobically fit individuals still have predispositions to cancer, but their incidence is generally much less than that of those who are not fit.
• The origin of cancer is damage to oxidative phosphorylation, which can be influenced by factors such as viral infectionsAn infection is like a party crasher in your body. It happens when harmful germs, like bacteria or viruses, invade your body tissues and start reproducing. This unwelcome invasion can disrupt your body’s normal functions, including your metabolism. • Synonyms: Well-documented synonyms for infection include: • Infestation (more common with parasites)… Read More, intermittent hypoxia, chronic inflammationChronic inflammation is like a fire smoldering in your body for a long time. It’s different from the acute inflammation you experience with a cut or a bruise, which is a short-term response to heal an injury. Chronic inflammation, however, lingers for months or even years, and while it may… Read More, and metabolic homeostasisMetabolic Homeostasis: Your Body’s Balancing Act for Optimal Health You may not have heard the term “metabolic homeostasis,” but your body performs this balancing act every day. It’s a bit like a symphony orchestra, where each instrument plays its part in perfect harmony to create a beautiful melody. In your… Read More.

34:05 Maintaining healthy mitochondria through diet and lifestyle reduces the probability of getting cancer.

• Observations of Aboriginal tribes and traditional groups show extremely rare cases of cancer due to their healthy diet and lifestyle.
• Evolutionary history suggests that a Paleolithic diet and lifestyle, with minimal processed foods and high carbohydrates, align with reduced cancer risk.

38:16 Blood markers provide insights into metabolic health and disease risk.

• Triglyceride levels indicate cardiovascular disease risk, low is good, high is bad.
• Other markers such as HDLThink of cholesterol as tiny packages traveling through your blood vessels, much like cars on a highway. There are two main types: LDL (“bad” cholesterol) and HDL (“good” cholesterol). HDL is like a helpful garbage truck that picks up extra cholesterol from your arteries and takes it back to the… Read More, LDLImagine your blood vessels as highways, and cholesterol as tiny packages traveling on those highways. There are two main types of cholesterol “delivery trucks”: • HDL (High-Density Lipoprotein): The “good” cholesterol. Think of it as a garbage truck, picking up extra cholesterol and taking it to the liver for recycling or removal. •… Read More, insulin levels, and glucose levels can also reveal metabolic issues.

40:10 Drug pricing in the cancer treatment industry is unethical.

• Parasite drug albendazole is priced at 50 cents in India, but in the US, it’s $350 per tablet.
• Combining drugs with lifestyle changes and diet has shown significant therapeutic benefits in managing cancer and improving overall health.

44:01 Metabolic treatment has extended the lives of terminal cancer patients.

• Patients in clinical trialsUnveiling the World of Clinical Trials: Your Guide to Understanding Research Participation Imagine a group of explorers venturing into uncharted territory, seeking new discoveries that could benefit humanity. In the world of medicine, clinical trials are those expeditions, carefully designed studies that test the safety and effectiveness of new drugs,… Read More are surviving longer with a good quality of life.
• Lack of funding and awareness hinders widespread adoption of metabolic treatments.

45:46 Doctors lack understanding of cancer biology

• Many doctors are clueless about the biology of the disease they’re treating.
• The focus on genetic targets in cancer treatment has limitations and risks.

49:18 Ketogenic approach can be used for effective treatment of cancer

• Ketogenic approach can help shrink cancer and making it more manageable, improving the effectiveness of surgery
• Water-only fasting and reducing carbohydrate intake can lower glucose levels and have therapeutic effects

51:11 Our natural state is unaddicted to glucose or maybe we were addicted, we just didn’t have access to it.

• Evolution as a species that was never addicted to glucose.
• The risk of consuming highly processed carbohydrates throughout the year.

55:06 Metabolic therapyTherapy is a broad term encompassing various treatment approaches aimed at improving health and well-being. It’s like a toolkit with various tools designed to address specific ailments and promote healing. While often associated with mental health, therapy extends far beyond the mind, encompassing physical and medical treatments as well. Etymology… Read More as an effective cancer treatment

• Current cancer treatments have severe adverse effects on the body and need improvement.
• Resistance and lack of discussion on metabolic therapy as a standard of careKey Sections to Include:Understanding Standards of Care: Your Guide to Safe and Effective Healthcare Imagine embarking on a road trip without a map or GPS. You’d likely get lost, make wrong turns, and potentially encounter dangerous situations. In the realm of healthcare, standards of care serve as a roadmap, guiding… Read More by medical professionals.

57:07 Adapting diet for metabolic treatment

• Different diets can be used to get into the metabolic treatment zone, with challenges for vegans and carnivores.
• Water only fasting can bring one into a state of therapeutic ketosis; dosage timing and scheduling are important for perfecting the treatment.

1:00:56 Dr. Thomas SeyfriedA Boston College professor specializing in cancer biology and metabolic theory, participated in a groundbreaking study. emphasizes the openness and transparency of his research work and funding sources.

• He highlights that all his publications can be easily accessed online, promoting the transparency of his work.
• He mentions that most of his research support comes from private foundations and philanthropy, with the aim of resolving cancer as a manageable disease.

1:02:47 Understanding patient metabolism is crucial for personalized cancer treatment.

• Knowledge of the patient’s metabolism can guide the dosage, timing, and scheduling of treatment without toxicity.
• Physicians need to retrain and work with a team to implement metabolic treatments effectively.

1:06:32 Fasting and a ketogenic diet are essential for optimizing metabolic function and may have anti-cancer benefits.

• Intermittent fasting for 1-3 days a month or 3-5 days a quarter can optimize metabolic function and promote longevity.
• Extended water fasts not only have fasting and longevity benefits but also ketogenic benefits, which may prove to be anti-cancer.

1:08:14 Processed carbohydrates drive blood sugar constantly

• Different types of carbohydrates have different biochemicalThe term “biochemical” simply means relating to the chemical reactions happening within living organisms. Imagine tiny factories inside your body constantly whirring away, and biochemical reactions are the instructions that keep those factories running smoothly. Etymology: The word is a combination of two Greek words: Bio, meaning “life” Chemical: referring… Read More responses in the body
• Chronic exposure to certain foods can create a specific state in the body

Please read: Although there have been miracles in improvement and quality of life, the press-pulse therapeutic strategy for for cancer is still in its early stages of development and agreement within medical communities. This website was created for information and entertainment purposes only.This website is not intended to be used for diagnosis, treatment, or as a replacement for the guidance of your qualified healthcare practitioner. Please speak with a medical expert before making any decisions pertaining to your health.